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Non Hodgkin Lymphoma (Indolent B-NHL) Panel - Paraffin pin


Methodology: FISH

Clinical Significance:
These FISH studies identify the genetic alteration characteristic of several major categories of non Hodgkin B cell lymphoma. These include the t(14;18) IGH/BCL2 and BCL6 family of rearrangements identified in follicular lymphomas, the t(11;14) identified in mantle cell lymphoma, and MALT1 gene rearrangements that are identified in a subset of marginal zone B cell lymphomas. The identification of an IGH rearrangement in isolation can also aid in the diagnosis of atypical lymphoid proliferations even when its translocation partner is not elucidated.


Disease State:

CPT Code(s): 88374x5 (reference only; CPTs may vary)

Turnaround Time: Within 4-6 business days of receipt

Schedule: Monday - Friday

Specimen Requirements:
• Formalin-fixed, paraffin-embedded tissue block or cell block - OR - • Minimum of 5 unstained slide cut at 4µm for each test requested