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p53 pin



Methodology: IHC

Clinical Significance:
Identifies: The p53 gene product, a tumor suppressor gene product which has been referred to as the “guardian of the genome” owing to its role in preventing genome mutation. Overexpression of p53 correlates with the presence of p53 mutations and can serve as a marker of malignancy. Subcellular Localization: Nuclear

Organ: Breast

Disease State: Diffuse Large B Cell Lymphoma

CPT Code(s): 88342 or 88341 (reference only; CPTs may vary)

Turnaround Time: Within 1-2 business days of receipt

Schedule: Monday - Friday

Specimen Requirements:
• Formalin-fixed, paraffin-embedded (FFPE) tissue block or cell block - OR - • 1 unstained slide for each test requested plus 3-4 additional unstained slides cut at 4µm