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p53 pin



Methodology: IHC

Clinical Significance:
Identifies: The p53 gene product, a tumor suppressor gene product which has been referred to as the “guardian of the genome” owing to its role in preventing genome mutation. Overexpression of p53 correlates with the presence of p53 mutations and can serve as a marker of malignancy. Subcellular Localization: Nuclear

Organ: Breast

Disease State: Diffuse Large B Cell Lymphoma

CPT Code(s): 88342 or 88341. The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Turnaround Time: Within 1-2 business days of receipt

Schedule: Monday - Friday

Specimen Requirements:
• Formalin-fixed, paraffin-embedded (FFPE) tissue block or cell block - OR - • 1 unstained slide for each test requested plus 3-4 additional unstained slides cut at 4µm