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p57-Kip2 pin



Methodology: IHC

Clinical Significance:
Identifies: A paternally imprinted protein, expression of which is lost in cytotrophoblasts of molar pregnancy, i.e., complete mole. The combination of analysis of p57 expression and ploidy (e.g., by FISH) can help define complete moles, incomplete moles, and hydropic normal villi. Subcellular Localization: Nuclear

Organ: OB/GYN

Disease State: Molar Pregnancy

CPT Code(s): 88342 or 88341 (reference only; CPTs may vary)

Turnaround Time: Within 1-2 business days of receipt

Schedule: Monday - Friday

Specimen Requirements:
• Formalin-fixed, paraffin-embedded (FFPE) tissue block or cell block - OR - • 1 unstained slide for each test requested plus 3-4 additional unstained slides cut at 4µm