Methodology: IHC

Clinical Significance:
Identifies: p63, a gene in the p53 family, that is expressed in myoepithelial cells, squamous and transitional epithelial cells, and the basal layer of prostate and other epithelial tissues. Identification of p63, or its absence, can be useful in identifying the presence of invasive carcinoma in breast and prostate, as well as the identification of squamous and transitional cell carcinomas. Subcellular Localization: Nuclear

Organ: Lung

Disease State: Carcinomas of Unknown Primary

CPT Code(s): 88342 or 88341. The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Turnaround Time: Within 1-2 business days of receipt

Schedule: Monday - Friday

Specimen Requirements:
• Formalin-fixed, paraffin-embedded (FFPE) tissue block or cell block - OR - • 1 unstained slide for each test requested plus 3-4 additional unstained slides cut at 4µm