Alternate Test Names:
Identifies: A nuclear protein expressed throughout B cell maturation prior to the plasma cell stage, at which point it is no longer expressed. PAX-5 is strongly expressed in the great majority of mature and immature B cell neoplasms, and in nodular lymphocyte predominance Hodgkin lymphoma. PAX-5 is expressed at decreased intensity in classical Hodgkin's lymphoma, and is not expressed in the great majority of plasma cell neoplasms.
Subcellular Localization: Nuclear
CPT Code(s): 88342 or 88341 (reference only; CPTs may vary)
Turnaround Time: Within 1-2 business days of receipt
Schedule: Monday - Friday
• Formalin-fixed, paraffin-embedded (FFPE) tissue block or cell block - OR -
• 1 unstained slide for each test requested plus 3-4 additional unstained slides cut at 4µm