Methodology: IHC

Clinical Significance:
Identifies: A nuclear protein expressed throughout B cell maturation prior to the plasma cell stage, at which point it is no longer expressed. PAX-5 is strongly expressed in the great majority of mature and immature B cell neoplasms, and in nodular lymphocyte predominance Hodgkin lymphoma. PAX-5 is expressed at decreased intensity in classical Hodgkin's lymphoma, and is not expressed in the great majority of plasma cell neoplasms. Subcellular Localization: Nuclear

Organ:

Disease State: B Cell Non-Hodgkin Lymphoma (not otherwise classified)

CPT Code(s): 88342 or 88341. The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Turnaround Time: Within 1-2 business days of receipt

Schedule: Monday - Friday

Specimen Requirements:
• Formalin-fixed, paraffin-embedded (FFPE) tissue block or cell block - OR - • 1 unstained slide for each test requested plus 3-4 additional unstained slides cut at 4µm