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PAX-6 pin



Methodology: IHC

Clinical Significance:
Identifies: PAX-6 is a member of the paired box protein family, and is a sensitive marker of pancreatic endocrine neoplasms. However, there is a lack of specificity as PAX-6 is also expressed by other neuroendocrine neoplasms and even some non-neuroendocrine tumors (e.g., endometrial and ovarian carcinomas). Subcellular Localization: Nuclear

Organ: Pancreas

Disease State:

CPT Code(s): 88342 or 88341 (reference only; CPTs may vary)

Turnaround Time: Within 1-2 business days of receipt

Schedule: Monday - Friday

Specimen Requirements:
• Formalin-fixed, paraffin-embedded (FFPE) tissue block or cell block - OR - • 1 unstained slide for each test requested plus 3-4 additional unstained slides cut at 4µm