Podoplanin (D2-40) pin

IHC

Podoplanin (D2-40)

Alternate Test Names:
D240

Methodology: IHC

Clinical Significance:
Identifies: Podoplanin, a marker of lymphatic endothelium, as well as neoplasms such as Kaposi’s sarcoma. In the context of epithelial tumors, podoplanin has also been demonstrated to be a highly sensitive marker of mesothelium and mesothelioma, complementing other markers such as calretinin and the Wilms tumor gene product.

Subcellular Localization: Membranous and cytoplasmic

Organ: Lung

Disease State: Follicular Dendritic Cell Sarcoma, Mesothelioma vs. Adenocarcinoma

CPT Code(s): 88342 or 88341 (reference only; CPTs may vary)

Turnaround Time: Within 1-2 business days of receipt

Schedule: Monday - Friday

Specimen Requirements:
• Formalin-fixed, paraffin-embedded (FFPE) tissue block or cell block - OR -
• 1 unstained slide for each test requested plus 3-4 additional unstained slides cut at 4µm

Tech Only