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IHC
Alternate Test Names:
S100
Methodology: IHC
Clinical Significance:
Identifies: A nuclear and cytoplasmic marker of a wide subset of tumors, but traditionally employed as a sensitive marker of melanoma, glial and schwann cell tumors.
Subcellular Localization: Cytoplasmic
Organ: Skin & Mucosa
Disease State: Langerhans Cell Histiocytosis, Large Cell Undifferentiated Malignant Neoplams, Melanoma, Spindle Cell Tumors / Sarcoma Subtyping
CPT Code(s): 88342 or 88341 (reference only; CPTs may vary)
Turnaround Time: Within 1-2 business days of receipt
Schedule: Monday - Friday
Specimen Requirements:
• Formalin-fixed, paraffin-embedded (FFPE) tissue block or cell block - OR -
• 1 unstained slide for each test requested plus 3-4 additional unstained slides cut at 4µm