Alternate Test Names:
S100

Methodology: IHC

Clinical Significance:
Identifies: A nuclear and cytoplasmic marker of a wide subset of tumors, but traditionally employed as a sensitive marker of melanoma, glial and schwann cell tumors.

Subcellular Localization: Cytoplasmic

Organ: Skin & Mucosa

Disease State: Langerhans Cell Histiocytosis, Large Cell Undifferentiated Malignant Neoplams, Melanoma, Spindle Cell Tumors / Sarcoma Subtyping

CPT Code(s): 88342 or 88341 (reference only; CPTs may vary)

Turnaround Time: Within 1-2 business days of receipt

Schedule: Monday - Friday

Specimen Requirements:
• Formalin-fixed, paraffin-embedded (FFPE) tissue block or cell block - OR -
• 1 unstained slide for each test requested plus 3-4 additional unstained slides cut at 4µm