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IHC
Methodology: IHC
Clinical Significance:
Identifies: SALL4 is a very sensitive marker for germ cell tumors, including seminoma, embryonal carcinoma, yolk sac tumor, and choriocarcinoma. SALL4 aLso shows high specificity for germ cell tumors, although positive in a subset of gastric carcinomas.
Subcellular Localization: Nuclear
Organ: OB/GYN
Disease State: Large Cell Undifferentiated Malignant Neoplams
CPT Code(s): 88342 or 88341 (reference only; CPTs may vary)
Turnaround Time: Within 1-2 business days of receipt
Schedule: Monday - Friday
Specimen Requirements:
• Formalin-fixed, paraffin-embedded (FFPE) tissue block or cell block - OR -
• 1 unstained slide for each test requested plus 3-4 additional unstained slides cut at 4µm