Alternate Test Names:
SALL-4

Methodology: IHC

Clinical Significance:
Identifies: SALL4 is a very sensitive marker for germ cell tumors, including seminoma, embryonal carcinoma, yolk sac tumor, and choriocarcinoma. SALL4 aLso shows high specificity for germ cell tumors, although positive in a subset of gastric carcinomas.

Subcellular Localization: Nuclear

Organ: Genitourinary, OB/GYN, Ovary, Testis

Disease State: Germ Cell Tumors, Large Cell Undifferentiated Malignant Neoplams

CPT Code(s): 88342 or 88341 (reference only; CPTs may vary)

Turnaround Time: Within 1-2 business days of receipt

Schedule: Monday - Friday

Specimen Requirements:
• Formalin-fixed, paraffin-embedded (FFPE) tissue block or cell block - OR -
• 1 unstained slide for each test requested plus 3-4 additional unstained slides cut at 4µm