Alternate Test Names:
SF1

Methodology: IHC

Clinical Significance:
Nuclear localization of SF-1 can be used to distinguish sex cord-stromal tumors (SCST) from non-sex cord-stromal tumors (e.g., borderline tumors, serous carcinomas, etc.) and is therefore useful in the differential diagnosis of these neoplasms. Antibodies to SF-1 should be run in a panel with other sex cord-stromal tumor markers, such as inhibin and calretinin.

Subcellular localization: Nuclear

Organ: Genitourinary, OB/GYN, Ovary, Pituitary, Testis

Disease State:

CPT Code(s): 88342 or 88341 (reference only; CPTs may vary)

Turnaround Time: Within 1-2 business days of receipt

Schedule: Monday - Friday

Specimen Requirements:
• Formalin-fixed, paraffin-embedded (FFPE) tissue block or cell block - OR -
• 1 unstained slide for each test requested plus 3-4 additional unstained slides cut at 4µm