Identifies: Smoothelin, a marker of terminally differentiated smooth muscle cells, relatively specific for the muscularis propria (positive) compared with the muscularis mucosae (largely negative). Used to assess the degree of invasion of colorectal and bladder carcinomas, particularly in small biopsies.
Subcellular Localization: Cytoplasmic
CPT Code(s): 88342 or 88341 (reference only; CPTs may vary)
Turnaround Time: Within 1-2 business days of receipt
Schedule: Monday - Friday
• Formalin-fixed, paraffin-embedded (FFPE) tissue block or cell block - OR -
• 1 unstained slide for each test requested plus 3-4 additional unstained slides cut at 4µm