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SOX11 pin



Methodology: IHC

Clinical Significance:
SOX11 is a transcription factor expressed in almost all cases of mantle cell lymphoma (MCL), including the rare entity cyclin D1-negative MCL. It is not expressed in potential MCL mimics such as atypical chronic lymphocytic leukemia / small lymphocytic lymphoma (CLL/SLL), follicular lymphoma, and marginal zone lymphoma (Soldini D, et al. Am J Surg Path 38:86-93, 2014). Subcellular Localization: Nuclear

Organ: Blood/Bone Marrow

Disease State: Mantle Cell Lymphoma

CPT Code(s): 88342 or 88341. The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Turnaround Time: Within 1-2 business days of receipt

Schedule: Monday - Friday

Specimen Requirements:
• Formalin-fixed, paraffin-embedded (FFPE) tissue block or cell block - OR - • 1 unstained slide for each test requested plus 3-4 additional unstained slides cut at 4µm