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SS18-SYT-synovial sarcoma-X18 pin


SS18-SYT-synovial sarcoma-X18

Methodology: FISH

Clinical Significance:
This sensitive breakapart assay detects any translocation involving the SYT gene. The most common of these translocations is the t(X;18) that juxtaposes the SYT gene with the SS18 gene and is the hallmark translocation of synovial sarcoma. Rearrangement of the SYT gene in these tumors can be detected in over 90% of cases. Evaluation for an SYT rearrangement is thus a useful test when synovial sarcoma is a diagnostic consideration. Probe type: Dual color breakapart

Organ: Soft Tissue

Disease State: Spindle Cell Tumors / Sarcoma Subtyping

CPT Code(s): 88374. The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Turnaround Time: Within 4-6 business days of receipt

Schedule: Monday - Friday

Specimen Requirements:
• Formalin-fixed, paraffin-embedded tissue block or cell block - OR - • Minimum of 5 unstained slide cut at 4µm for each test requested