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Synaptophysin pin



Methodology: IHC

Clinical Significance:
A highly sensitive and specific marker of neural and neuroendocrine cells and tumors. Shows superior sensitivity to chromogranin A in the context of high grade neuroendocrine carcinomas. Also expressed in PNET/ES and other tumors showing neural differentiation.

Subcellular Localization: Cytoplasmic, finely granular

Organ: Lung

Disease State: Small, Blue, Round Cell Tumors

CPT Code(s): 88342 or 88341 (reference only; CPTs may vary)

Turnaround Time: Within 1-2 business days of receipt

Schedule: Monday - Friday

Specimen Requirements:
• Formalin-fixed, paraffin-embedded (FFPE) tissue block or cell block - OR - • 1 unstained slide for each test requested plus 3-4 additional unstained slides cut at 4µm