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t(14;18) IGH/MALT pin

FISH

Methodology: FISH

Clinical Significance:
This dual color dual fusion FISH assay secifically detects the t(14;18)(q32;q21). This translocation, which juxtaposes the MALT1 gene on chromosome 18q21 with the IGH chain gene on 14q32, is detected in approximately 10% of patients with MALT lymphomas, namely in MALT lymphomas of the liver, skin, ocular adnexa, and salivary gland, but typically does not occur in MALT lymphomas of the stomach, intestine, lung, thyroid, or breast. Probe type: Dual color, dual fusion translocation

Organ: Blood/Bone Marrow

Disease State: B Cell Non-Hodgkin Lymphoma (not otherwise classified)

CPT Code(s): 88374. The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Turnaround Time: Within 4-6 business days of receipt

Schedule: Monday - Friday

Specimen Requirements:
• Formalin-fixed, paraffin-embedded tissue block or cell block - OR - • Minimum of 5 unstained slide cut at 4µm for each test requested