Alternate Test Names:
TCR beta F1; TCRßF1; TCRBF1

Methodology: IHC

Clinical Significance:
Identifies: The alpha/beta chain of the T cell receptor, present on normal T lymphocytes and most T cell neoplasms, e.g., peripheral T cell lymphoma (PTCL), T-lymphoblastic lymphoma/leukemia, mycosis fungoides. Negative on normal B cells, B cell neoplasms, anaplastic large cell lymphoma (ALCL), and NK/T cell neoplasms.

Subcellular Localization: Membranous

Organ:

Disease State: Angioimmunoblastic T Cell Lymphoma, Peripheral T Cell Lymphoma, NOS (of Large Cell Type)

CPT Code(s): 88342 or 88341 (reference only; CPTs may vary)

Turnaround Time: Within 1-2 business days of receipt

Schedule: Monday - Friday

Specimen Requirements:
• Formalin-fixed, paraffin-embedded (FFPE) tissue block or cell block - OR -
• 1 unstained slide for each test requested plus 3-4 additional unstained slides cut at 4µm