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IHC
Methodology: IHC
Clinical Significance:
Identifies: Terminal deoxynucleotidyltransferase, a specialized DNA polymerase expressed in immature, pre-B, pre-T lymphoid cells, and also the majority of precursor B- and T-lymphoblastic leukemias/lymphomas. TdT is aberrantly expressed in a small subset of acute myeloid leukemias.
Subcellular Localization: Nuclear
Organ:
Disease State: Small, Blue, Round Cell Tumors
CPT Code(s): 88342 or 88341 (reference only; CPTs may vary)
Turnaround Time: Within 1-2 business days of receipt
Schedule: Monday - Friday
Specimen Requirements:
• Formalin-fixed, paraffin-embedded (FFPE) tissue block or cell block - OR -
• 1 unstained slide for each test requested plus 3-4 additional unstained slides cut at 4µm