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TFE3 (test is no longer offered) pin

IHC

TFE3 (test is no longer offered)

Methodology: IHC

Clinical Significance:
Identifies: Transcription factor E3, a member of the helix-loop-helix family of transcription factor. Overexpression of TFE3 results from the presence of a chromosomal translocation involving Xp11, present in alveolar soft part sarcoma and a subset of “translocation” renal cell carcinomas. Subcellular Localization: Nuclear

Organ: Genitourinary Tumors

Disease State:

CPT Code(s): 88342 or 88341

Turnaround Time: Within 1-2 business days of receipt

Schedule: Monday - Friday

Specimen Requirements:
• Formalin-fixed, paraffin-embedded (FFPE) tissue block or cell block - OR - • 1 unstained slide for each test requested plus 3-4 additional unstained slides cut at 4µm