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FISH
Methodology: FISH
Clinical Significance:
Translocations involving the TFE3 gene at Xp11.2 have been described in a subset of tumors including renal cell carcinomas as well as in alveolar soft part sarcoma (see reference 3). TFE3 FISH is therefore indicated where the presence of a TFE3 translocation is being considered during the pathologic evaluation of the tumor.
Organ: Kidney
Disease State:
CPT Code(s): 88374 (reference only; CPTs may vary)
Turnaround Time: Within 4-6 business days of receipt
Schedule: Monday - Friday
Specimen Requirements:
• Formalin-fixed, paraffin-embedded tissue block or cell block - OR -
• Minimum of 5 unstained slide cut at 4µm for each test requested