Methodology: FISH

Clinical Significance:
Translocations involving the TFE3 gene at Xp11.2 have been described in a subset of tumors including renal cell carcinomas as well as in alveolar soft part sarcoma (see reference 3). TFE3 FISH is therefore indicated where the presence of a TFE3 translocation is being considered during the pathologic evaluation of the tumor.

Organ: Kidney

Disease State:

CPT Code(s): 88374. The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Turnaround Time: Within 4-6 business days of receipt

Schedule: Monday - Friday

Specimen Requirements:
• Formalin-fixed, paraffin-embedded tissue block or cell block - OR - • Minimum of 5 unstained slide cut at 4µm for each test requested