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Thrombomodulin pin



Methodology: IHC

Clinical Significance:
Identifies: Thrombomodulin (CD141), an integral membrane protein expressed on the surface of endothelial cells, and hence a marker of endothelial cells and vascular neoplasms. Thromobomodulin is also expressed on mesothelial cells, and may be used as part of a broader panel of antibodies in the distinction of mesothelioma from adenocarcinoma. Subcellular Localization: Membranous


Disease State:

CPT Code(s): 88342 or 88341 (reference only; CPTs may vary)

Turnaround Time: Within 1-2 business days of receipt

Schedule: Monday - Friday

Specimen Requirements:
• Formalin-fixed, paraffin-embedded (FFPE) tissue block or cell block - OR - • 1 unstained slide for each test requested plus 3-4 additional unstained slides cut at 4µm