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Identifies: A dimeric protein produced by and used within the thyroid gland. While it is an excellent marker of metastatic thyroid carcinoma, technical issues with anti-thyroglobulin antibodies, often producing nonspecific signal, make the combination of TTF-1 and PAX-8 expression a better marker of these tumors.
Subcellular Localization: Cytoplasmic
CPT Code(s): 88342 or 88341 (reference only; CPTs may vary)
Turnaround Time: Within 1-2 business days of receipt
Schedule: Monday - Friday
• Formalin-fixed, paraffin-embedded (FFPE) tissue block or cell block - OR -
• 1 unstained slide for each test requested plus 3-4 additional unstained slides cut at 4µm