Methodology: IHC

Clinical Significance:
Identifies: A dimeric protein produced by and used within the thyroid gland. While it is an excellent marker of metastatic thyroid carcinoma, technical issues with anti-thyroglobulin antibodies, often producing nonspecific signal, make the combination of TTF-1 and PAX-8 expression a better marker of these tumors. Subcellular Localization: Cytoplasmic

Organ: Thyroid

Disease State:

CPT Code(s): 88342 or 88341. The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Turnaround Time: Within 1-2 business days of receipt

Schedule: Monday - Friday

Specimen Requirements:
• Formalin-fixed, paraffin-embedded (FFPE) tissue block or cell block - OR - • 1 unstained slide for each test requested plus 3-4 additional unstained slides cut at 4µm