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Transthyretin identifies a serum protein produced by the liver and choroid plexus. It forms the basis of one subtype of amyloid, identification of which, and distinction from immunoglobulin light chain derived amyloids, can be made by immunohistochemistry. Transthyretin can also serve as a marker of choroid plexus tumors.
Subcellular Localization: Cytoplasmic and in extracellular spaces
Disease State: Amyloid Type Analysis
CPT Code(s): 88342 or 88341 (reference only; CPTs may vary)
Turnaround Time: Within 1-2 business days of receipt
Schedule: Monday - Friday
• Formalin-fixed, paraffin-embedded (FFPE) tissue block or cell block - OR -
• 1 unstained slide for each test requested plus 3-4 additional unstained slides cut at 4µm