Tyrosinase pin

IHC

Tyrosinase

Methodology: IHC

Clinical Significance:
Identifies: The rate limiting enzyme for controlling the production of melanin, and thus a marker of melanocytic cells and tumors. A less sensitive marker of melanoma than gp100 (identified by HMB-45) and MART-1.

Subcellular Localization: Cytoplasmic

Organ: Skin & Mucosa

Disease State: Melanoma

CPT Code(s): 88342 or 88341 (reference only; CPTs may vary)

Turnaround Time: Within 1-2 business days of receipt

Schedule: Monday - Friday

Specimen Requirements:
• Formalin-fixed, paraffin-embedded (FFPE) tissue block or cell block - OR -
• 1 unstained slide for each test requested plus 3-4 additional unstained slides cut at 4µm

Tech Only