Methodology: IHC

Clinical Significance:
Identifies: A transmembrane protein that is a specific marker of transitional cell epithelium and tumors. While highly specific, uroplakin is a marker of low sensitivity for urothelial carcinomas.

Subcellular Localization: Membranous

Organ: Genitourinary

Disease State: Carcinomas of Unknown Primary

CPT Code(s): 88342 or 88341 (reference only; CPTs may vary)

Turnaround Time: Within 1-2 business days of receipt

Schedule: Monday - Friday

Specimen Requirements:
• Formalin-fixed, paraffin-embedded (FFPE) tissue block or cell block - OR -
• 1 unstained slide for each test requested plus 3-4 additional unstained slides cut at 4µm