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Villin pin

IHC

Villin

Methodology: IHC

Clinical Significance:
Identifies: An actin binding protein that is a marker of carcinomas of GI tract origin. Villin, along with CDX2, is a highly specific and fairly sensitive marker of colorectal as well as “noncolorectal GI tract” (e.g., pancreatobiliary tract) derived carcinomas. In the latter tumors, a brush border pattern is characteristic. A subset of lung adenocarcinomas are also villin positive. Subcellular Localization: Cytoplasmic, membranous, “brush border” pattern

Organ: Liver

Disease State: Carcinomas of Unknown Primary

CPT Code(s): 88342 or 88341. The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Turnaround Time: Within 1-2 business days of receipt

Schedule: Monday - Friday

Specimen Requirements:
• Formalin-fixed, paraffin-embedded (FFPE) tissue block or cell block - OR - • 1 unstained slide for each test requested plus 3-4 additional unstained slides cut at 4µm