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IHC
Methodology: IHC
Clinical Significance:
Identifies: von Willebrand factor (often erroneously referred to as "Factor VIII") is synthesized by endothelial cells and stored in the Weibel-Palade granules. von Willebrand factor can be employed as a marker of vascular neoplasms as well as a marker of megakaryocytic differentiation.
Subcellular Localization: Cytoplasmic
Organ:
Disease State: Spindle Cell Tumors / Sarcoma Subtyping
CPT Code(s): 88342 or 88341 (reference only; CPTs may vary)
Turnaround Time: Within 1-2 business days of receipt
Schedule: Monday - Friday
Specimen Requirements:
• Formalin-fixed, paraffin-embedded (FFPE) tissue block or cell block - OR -
• 1 unstained slide for each test requested plus 3-4 additional unstained slides cut at 4µm